Table 2.

Results of the univariable and multivariable logistic regression analyses for the association between age, sex, multimorbidity and polypharmacy with potentially inappropriate prescribing

Explanatory variable	Univariable model	P value	Multivariable model*	P value
	OR (95% CI)		OR (95% CI)
Age (years)	1.02 (0.99 to 1.06)	0.22	0.99 (0.94 to 1.03)	0.54
Females (vs males)	1.18 (0.70 to 1.96)	0.54	1.47 (0.84 to 2.59)	0.18
Multimorbidity†	3.24 (1.93 to 5.44)	<0.01	2.08 (1.16 to 3.73)	<0.01
Polypharmacy‡	5.52 (3.10 to 9.86)	<0.01	4.81 (2.52 to 9.16)	<0.01

*Adjusted for age, sex, multimorbidity, polypharmacy and country.

†Multimorbidity: defined as the co-occurrence of three or more chronic conditions.

‡Polypharmacy: defined as five or more regular medicines.