Fig 1. Variation in host responses to C. neoformans infections.
(A) A measured intracellular proliferation rate (IPR) for each donor showing median of at least 2 biological repeats each (median = 0.53, mean = 0.6307, SD = 0.5275 and Coefficient of variation = 83.64%). (B) Variable rates of vomocytosis observed between and within donors showing median of at least 2 biological repeats each (median = 41.11%, mean = 41.55%, SD = 15.53 and Coefficient of variation = 37.37%). (C) Correlation between intracellular parasitism and non-lytic expulsion events (R square = 0.2501, P-value = 0.0005). Each point on the graph represents data from a single blood donation. Since not all participants were available to provide four repeat donations across the study period, the number of repeated samples varies from donor to donor.
