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. 2018 Mar 29;13(3):e0194598. doi: 10.1371/journal.pone.0194598

Table 1. The estimated annual incidence (per 100,000 persons) and case-fatality rate of invasive pneumococcal disease (IPD), pneumococcal pneumonia (PP) and community-acquired pneumonia (CAP).

Incidence rate (95% confidence interval)
Total 2011 2012 2013 2014 p-value
IPD 4.8 (4.8–4.9) 6.5 (6.4–6.5) 4.2 (4.2–4.3) 4.1 (4.1–4.2) 4.4 (4.4–4.5) 0.161
PP 44.3 (44.3–44.4) 42.2 (42.0–42.3) 42.6 (42.5–42.8) 43.1 (43.0–43.3) 49.4 (49.2–49.5) 0.104
CAP 307.7 (307.0–308.4) 288.7 (287.4–290.0) 297.8 (296.5–299.1) 336.0 (334.6–337.4) 309.6 (308.3–310.9) 0.005
Case-fatality rate (95% confidence interval)
IPD 30.8 (22.2–40.9) 28.1 (15.6–45.4) 31.6 (15.4–54.0) 36.8 (19.2–59.0) 28.6 (13.8–50.0) 0.836
PP 9.1 (7.4–11.3) 10.5 (7.1–15.4) 7.8 (4.8–12.5) 9.1 (5.8–13.9) 9.0 (5.9–13.3) 0.698
CAP 6.2 (5.6–6.8) 6.9 (5.7–8.3) 5.7 (4.6–7.1) 5.9 (4.8–7.2) 6.2 (5.1–7.6) 0.524