Table 3. Conspicuity scores.
T1w | T2w | ceT1w | SWI | FLAIR | DWI | |
---|---|---|---|---|---|---|
Lesions at first diagnosis MRI | ||||||
n of 720 | 699 | 706 | 712 | 496 | 673 | 510 |
mean CS | 1.77 | 1.82 | 2.91 | 1.94 | 2.32 | 1.42 |
±SD | 1.14 | 1.17 | 0.30 | 1.22 | 1.05 | 1.27 |
n(CS 0) | 124 (17.7%) | 143 (20.3%) | 0 (0%) | 104 (21.0%) | 72 (10.7%) | 191 (37.5%) |
n(CS 1) | 179 (25.6%) | 132 (18.7%) | 2 (0.3%) |
71 (14.3%) | 83 (12.3%) | 72 (14.1%) |
n(CS 2) | 131 (18.7%) | 143 (20.3%) | 60 (8.4%) | 72 (14.5%) | 75 (11.1%) | 91 (17.8%) |
n(CS 3) | 265 (37.9%) | 288 (40.8%) | 650 (91.3%) | 249 (50.2%) | 443 (65.8%) | 156 (30.6%) |
Lesions at pre-diagnosis MRI | ||||||
n of 33 | 33 | 33 | 33 | 23 | 32 | 24 |
mean CS | 0.48 | 0.18 | 1.82 | 0.39 | 0.56 | 0.17 |
±SD | 0.83 | 0.64 | 0.88 | 0.94 | 1.01 | 0.64 |
n(CS 0) | 22 (66.7%) | 30 (90.9%) | 0 (0%) | 19 (82.6%) | 22 (68.8%) | 22 (91.7%) |
n(CS 1) | 8 (24.2%) | 1 (3.0%) | 16 (48.5%) | 1 (4.3%) | 6 (18.8%) | 1 (4.2%) |
n(CS 2) | 1 (3.0%) | 1 (3.0%) | 7 (21.2%) | 1 (4.3%) | 0 (0%) | 0 (0%) |
n(CS 3) | 2 (6.1%) | 1 (3.0%) | 10 (30.3%) | 2 (8.7%) | 4 (12.5%) | 1 (4.2%) |
Lesions ≤ 5 mm diameter at first diagnosis MRI | ||||||
n | 385 | 390 | 391 | 270 | 377 | 293 |
mean CS | 1.33 | 1.2 | 2.72 | 1.46 | 1.77 | 0.83 |
±SD | 1.15 | 1.11 | 0.56 | 1.29 | 1.22 | 1.1 |
Leptomeningeal lesions | ||||||
n of 720 | 77 | 79 | 76 | 70 | 77 | 63 |
mean CS | 1.84 | 1.29 | 2.82 | 1.33 | 2.17 | 0.87 |
±SD | 1.12 | 1.15 | 0.48 | 1.34 | 1.12 | 1.08 |
Pachymeningeal lesions | ||||||
n of 720 | 18 | 19 | 19 | 17 | 19 | 17 |
mean CS | 2.06 | 2.11 | 3.00 | 2.35 | 2.58 | 1.82 |
±SD | 1.00 | 1.05 | 0.00 | 1.06 | 0.90 | 1.19 |
Amelanotic lesions | ||||||
n of 49 | 47 | 48 | 47 | 28 | 44 | 25 |
mean CS | 1.44 | 1.98 | 2.90 | 2.30 | 2.53 | 1.65 |
±SD | 1.21 | 1.00 | 0.31 | 0.97 | 0.94 | 1.27 |
Melanotic lesions | ||||||
n of 169 | 159 | 167 | 164 | 130 | 154 | 124 |
mean CS | 1.84 | 1.63 | 2.88 | 1.98 | 2.17 | 1.48 |
±SD | 1.13 | 1.22 | 0.32 | 1.23 | 1.13 | 1.30 |
Abbr.: n, number; CS, conspicuity score; SD, standard deviation; T1w, non-enhanced T1-weighted; T2w, T2-weighted; ceT1w, contrast-enhanced T1-weighted; SWI, susceptibility-weighted imaging; FLAIR, fluid-attenuated inversion recovery; DWI, diffusion-weighted imaging. Total number of lesions with confirmed melanotic / amelanotic primary tumor histology was 218/720 lesions overall.