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. 2018 Mar 29;13(3):e0194464. doi: 10.1371/journal.pone.0194464

Fig 8. The bistable switch in the core network depending on (a3, a7) parameters and at h = 6. Highlighted region is the parameters range, for which the switch-like behavior has existed.

Fig 8

Furthermore, the analysis indicated that a straight line a3 = a7 in the plane (a3, a7) divides it into two areas. When a3 < a7, there will be some A0, that upon A > A0 the cell is pluripotent, while at A < A0 the cell will differentiate. When a3 > a7, the cell has pluripotent state at all values A0.