Fig 6. Transition robustness.

(A) 100 randomly drawn states of the IGF/Wnt model were mutated by bit flip (point mutation) and their successor states were computed. The successor states of the mutated and the original states were then compared using the normalized Hamming distance (red line). The same was done for 100 randomly generated networks of the same size (histogram). The blue line shows the 95% quantile. (B) shows the same test for the IGF sub-network and (C) for the Wnt sub-network.