Table 4. Odds ratio and 95% confidence interval of association of SSS >4 and quintiles of TSH levels.
| Quintiles of TSH | Crude | Model 1 | Model 2 |
|---|---|---|---|
| Euthyroid, SCHypo, SCHyper (n=767) | |||
| SSS >4 | |||
| 1st (0.00–0.95 mIU/L) | 1.27 (0.69–2.34) | 1.37 (0.71–2.63) | 1.17 (0.59–2.33) |
| 2nd (0.96–1.32 mIU/L) | 1.13 (0.61–2.12) | 1.03 (0.53–2.00) | 0.94 (0.47–1.86) |
| 3rd (1.33–1.78 mIU/L) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| 4th (1.79–2.71 mIU/L) | 1.39 (0.76–2.55) | 1.23 (0.65–2.33) | 1.31 (0.68–2.53) |
| 5th (2.72–35.5 mIU/L) | 0.80 (0.41–1.56) | 0.89 (0.44–1.79) | 0.98 (0.48–2.02) |
| P (1st vs 3rd) | 0.451 | 0.346 | 0.651 |
| Euthyroid subjects (n=697) | |||
| SSS >4 | |||
| 1st (0.41–0.94 mIU/L) | 1.07 (0.57–2.03) | 1.15 (0.58–2.29) | 0.91 (0.44–1.88) |
| 2nd (0.95–1.28 mIU/L) | 1.05 (0.56–2.00) | 0.93 (0.47–1.82) | 0.78 (0.38–1.57) |
| 3rd (1.29–1.67 mIU/L) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| 4th (1.68–2.44 mIU/L) | 1.17 (0.62–2.19) | 1.06 (0.55–2.07) | 1.03 (0.52–2.04) |
| 5th (2.45–3.97 mIU/L) | 0.75 (0.38–1.48) | 0.77 (0.38–1.58) | 0.78 (0.37–1.63) |
| P (1st vs 3rd) | 0.829 | 0.683 | 0.789 |
SCHypo: subclinical hypothyroidism; SCHyper: subclinical hyperthyroidism. Model 1: adjusted for age, gender, race/skin color; Model 2: model 1 plus hypertension, diabetes mellitus, dyslipidemia, smoking, BMI, HDL-cholesterol, triglycerides, glomerular filtration rate by CKD-Epi (Chronic Kidney Disease Epidemiology Collaboration), and C-reactive protein.