Table 5. Odds ratio and 95% confidence interval of association of coronary artery disease and quintiles of free thyroxine (FT4).

Quintiles of FT4	Crude	Model 1	Model 2
Coronary artery disease (all=746)*
1st (0.8–1.00 ng/dL)	1.12 (0.72–1.75)	1.10 (0.68–1.78)	1.16 (0.70–1.90)
2nd (1.01–1.08 ng/dL)	1.04 (0.66–1.62)	1.06 (0.66–1.70)	1.03 (0.63–1.68)
3rd (1.09–1.16 ng/dL)	1.0 (reference)	1.0 (reference)	1.0 (reference)
4th (1.17–1.25 ng/dL)	1.09 (0.69–1.72)	0.98 (0.60–1.59)	0.95 (0.57–1.58)
5th (1.26–2.11 ng/dL)	1.12 (0.72–1.76)	1.02 (0.63–1.63)	0.90 (0.55–1.47)
P (1st vs 3rd)	0.626	0.687	0.571
SIS>4 (n=746)
1st (0.8–1.00 ng/dL)	1.13 (0.58–2.20)	1.23 (0.60–2.52)	1.39 (0.66–2.94)
2nd (1.01–1.08 ng/dL)	0.96 (0.48–1.93)	1.04 (0.50–2.16)	0.97 (0.45–2.10)
3rd (1.09–1.16 ng/dL)	1.0 (reference)	1.0 (reference)	1.0 (reference)
4th (1.17–1.25 ng/dL)	1.76 (0.93–3.33)	1.70 (0.87–3.33)	1.88 (0.93–3.78)
5th (1.26–2.11 ng/dL)	1.08 (0.55–2.12)	0.92 (0.45–1.88)	0.88 (0.42–1.87)
P (1st vs 3rd)	0.731	0.567	0.382
SSS>4 (n=746)
1st (0.8–1.00 ng/dL)	1.00 (0.52–1.94)	1.07 (0.53–2.16)	1.19 (0.58–2.46)
2nd (1.01–1.08 ng/dL)	1.16 (0.61–2.21)	1.28 (0.65–2.53)	1.24 (0.61–2.52)
3rd (1.09–1.16 ng/dL)	1.0 (reference)	1.0 (reference)	1.0 (reference)
4th (1.17–1.25 ng/dL)	1.95 (1.06–3.57)	1.92 (1.01–3.64)	2.07 (1.07–4.03)
5th (1.26–2.11 ng/dL)	0.96 (0.49–1.87)	0.82 (0.40–1.65)	0.81 (0.39–1.68)
P (1st vs 3rd)	0.992	0.842	0.638

^*All includes euthyroid, subclinical hypothyroidism and subclinical hyperthyroidism. Model 1: adjusted for age, gender, race/skin color; Model 2: model 1 plus hypertension, diabetes mellitus, dyslipidemia, smoking, BMI, HDL-cholesterol, triglycerides, glomerular filtration rate by CKD-Epi (Chronic Kidney Disease Epidemiology Collaboration), and C-reactive protein. SIS: segment involvement score; SSS: segment severity score.