Figure 2. Hypoxia treatment altered the expression of miR-448 and SIRT1 in nerve cells. A, Expression of miR-448 in AGE1.HN and PC12 cells with or without hypoxia treatment was determined by qRT-PCR. B, Expressions of SIRT1 mRNA and protein in AGE1.HN and PC12 cells with or without hypoxia treatment were analyzed by qRT-PCR and western blot, respectively. Data are reported as means±SD. *P<0.05 vs control (t-test).
