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. 2018 Feb 26;29(4):1182–1197. doi: 10.1681/ASN.2017080935

Figure 3.

Figure 3.

NBCe1-A KO, which causes spontaneous metabolic acidosis, prevents changes in urinary ammonia excretion despite excretion of urine that is more acidic than in WT mice. (A) Urinary ammonia excretion under basal conditions. There is no significant difference between WT and NBCe1-A KO mice (P=NS; n=29 and 25, respectively). (B) Basal urine pH in NBCe1-A KO mice is significantly more acidic than in WT mice (P<0.001; n=29 and 25, respectively).