Table 2.

Physiologic parameters after acid loading

Parameter	WT	NBCe1-A KO	P Value
Mean daily body wt, g/d	21.6±0.5 (23)	14.3±0.8 (17)	<0.001
Mean daily urine volume, ml/d	1.87±0.21 (23)	2.41±0.27 (17)	NS
Serum Na+, mmol/L	150±0 (23)	149±1 (16)	NS
Serum K+, mmol/L	3.89±0.07 (23)	3.57±0.13 (16)	<0.05
Serum HCO3−, mmol/L	20.8±0.7 (23)	6.1±0.2 (16)	<0.001

Numbers in parentheses reflect number of animals studied.