Table 3.

Intradialytic changes in CBF (ml/100 g per minute)

Brain Region	Before Start HD T1	After Start HDa T2	At the End of HDa T3	Dialysis Treatment Effectb
				T1 versus T3	T2 versus T3
Global	34.5±5.1	34.0±5.0	30.5±4.4	−4.1 (−7.3 to −0.9)c	−3.8 (−7.2 to −0.5)c
Regional
Frontal lobe	40.2±6.9	38.9±5.6	35.0±4.7	−5.1 (−9.5 to −0.6)c	−4.1 (−7.8 to −0.3)c
Parietal lobe	37.4±7.0	36.3±6.2	32.6±5.1	−4.7 (−8.7 to −0.8)c	−4.0 (−7.4 to −0.6)c
Temporal lobe	35.8±5.1	35.7±5.6	31.8±4.7	−4.0 (−7.4 to −0.6)c	−4.0 (−6.9 to −1.0)d
Occipital lobe	41.9±5.1	41.6±5.1	37.7±5.6	−4.4 (−8.4 to −0.3)c	−4.5 (−8.1 to −1.0)d
Cerebellum	43.3±6.8	44.8±7.4	38.4±6.2	−5.0 (−9.2 to −0.8)c	−6.3 (−10.0 to −2.6)e
Thalamus	47.3±7.2	48.1±8.4	41.7±8.3	−5.5 (−11.1 to 0.2)	−6.6 (−11.5 to −1.7)d

Data are presented as unadjusted mean±SD.

^aScan 2 and 3 were performed at mean 21 and 209 minutes after start of HD, respectively.

^bDialysis treatment effects are obtained from linear mixed effects models and presented as mean difference (95% CI).

^cP<0.05.

^dP<0.01.

^eP<0.001.