Table 1.
Metabochip Loci | Chr:BP | Gene | A1/A2 | Population | N | CAF | Beta | SE | P-value | HetP |
---|---|---|---|---|---|---|---|---|---|---|
rs2820436 (1q41) | 1:219640680 | LYPLAL1/ZC3H11B | A/C | Combined | 94255 | 0.3876 | 0.0049 | 0.0009 | 3.79E-08 | 0.65 |
AA | 35606 | 0.4782 | 0.0051 | 0.0015 | 8.34E-04 | NA | ||||
HA | 26046 | 0.4395 | 0.0062 | 0.0017 | 1.61E-04 | NA | ||||
AS | 14210 | 0.1952 | 0.0021 | 0.0021 | 3.20E-01 | NA | ||||
EA | 17859 | 0.3446 | 0.0024 | 0.0132 | 8.56E-01 | NA | ||||
NA | 534 | 0.3446 | 0.0024 | 0.0132 | 8.56E-01 | NA | ||||
rs10930502 (2q31.1) | 2:172890588 | METAP1D | A/G | Combined | 94256 | 0.6794 | 0.0048 | 0.0009 | 1.35E-07 | 0.94 |
AA | 35599 | 0.7000 | 0.004 | 0.0017 | 1.70E-02 | NA | ||||
HA | 26043 | 0.6555 | 0.0043 | 0.0018 | 1.40E-02 | NA | ||||
AS | 14220 | 0.3327 | 0.0056 | 0.0018 | 1.45E-03 | NA | ||||
EA | 17859 | 0.6971 | 0.0056 | 0.0021 | 8.89E-03 | NA | ||||
NA | 535 | 0.6794 | 0.0102 | 0.0137 | 4.56E-01 | NA |
Chr: chromosome, BP: base pair position hg19/GRCh37, A1: coded allele, A2: non-coded allele, CAF: coded allele frequency, StdErr=Standard Error, AS=Asian, AA=African American, HA=Hispanic American, EA=European American, NA=Native American, HetP: heterogeneity p-value,
fine-mapping regions for other traits (HDL, T2D, WHR).