Skip to main content
. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Arthritis Rheumatol. 2018 Mar 7;70(4):566–577. doi: 10.1002/art.40399

FIGURE 3. Co-IRs exhibit subject-specific activities in controlling lymphocyte cytokine production.

FIGURE 3

PBMCs from SSc and healthy subjects were stimulated with DCs from a healthy donor in the absence or presence of anti-PD-1, anti-TIGIT or anti-TIM blocking antibodies and supernatants analyzed with a 14 cytokine multiplex assay. Bar graphs show the amount (pg/ml) of each of the indicated cytokines produced by individual healthy and SSc donors. Dotted line indicates the level of total cytokine produced in the isotype control cultures.