Table 3.
Stepwise linear regression results
| DTI Analysis |
Diffusion Measure |
Microstructure | β | Standardized β | R2 |
|---|---|---|---|---|---|
| Single Echo | |||||
| λ1 | Constant | 1.78E-03 | |||
| Edema | 4.64E-06 | .990 | .980 | ||
|
| |||||
| Fibrosis | −1.08E-06 | −.046 | .983 | ||
|
| |||||
| Fiber Size | 1.55E-06 | .018 | .983 | ||
|
| |||||
| λ2 | Constant | 1.59E-04 | |||
| Fiber Size | 2.39E-04 | .670 | .449 | ||
|
| |||||
| Permeability | 5.77E-04 | .581 | .787 | ||
|
| |||||
| Fibrosis | 1.65E-05 | .168 | .815 | ||
|
| |||||
| Edema | 1.79E-06 | .091 | .823 | ||
|
| |||||
| λ3 | Constant | 2.02E-04 | |||
| Fiber Size | 2.22E-04 | .638 | .407 | ||
|
| |||||
| Permeability | 5.78E-04 | .597 | .763 | ||
|
| |||||
| Fibrosis | 1.68E-05 | .176 | .794 | ||
|
| |||||
| Edema | 1.23E-06 | .064 | .798 | ||
|
| |||||
| MD | Constant | 7.14E-04 | |||
| Fiber Size | 1.54E-04 | .646 | .417 | ||
|
| |||||
| Permeability | 3.85E-04 | .580 | .754 | ||
|
| |||||
| Edema | 2.55E-06 | .195 | .791 | ||
|
| |||||
| Fibrosis | 1.07E-05 | .164 | .818 | ||
|
| |||||
| FA | Constant | 7.49E-01 | |||
| Fiber Size | −1.14E-01 | −.661 | .437 | ||
|
| |||||
| Permeability | −2.59E-01 | −.539 | .727 | ||
|
| |||||
| Fibrosis | −7.95E-03 | −.168 | .755 | ||
|
| |||||
| Edema | 5.89E-04 | .062 | .759 | ||
|
| |||||
| Multi-Echo (Short T2) | |||||
| λ1 | Constant | 1.77E-03 | |||
| Permeability | −3.16E-06 | −.132 | .018 | ||
|
| |||||
| Fiber Size | −7.72E-07 | −.090 | .026 | ||
|
| |||||
| Edema | 2.52E-08 | .054 | .029 | ||
|
| |||||
| λ2 | Constant | −2.91E-04 | |||
| Fiber Size | 3.99E-04 | .873 | .762 | ||
|
| |||||
| Permeability | 4.11E-04 | .324 | .866 | ||
|
| |||||
| Fibrosis | 4.20E-06 | .033 | .867 | ||
|
| |||||
| λ3 | Constant | −2.82E-04 | |||
| Fiber Size | 3.91E-04 | .870 | .756 | ||
|
| |||||
| Permeability | 4.07E-04 | .325 | .862 | ||
|
| |||||
| Fibrosis | 4.54E-06 | .037 | .864 | ||
|
| |||||
| MD | Constant | 3.99E-04 | |||
| Fiber Size | 2.63E-04 | .871 | .758 | ||
|
| |||||
| Permeability | 2.72E-04 | .323 | .863 | ||
|
| |||||
| Fibrosis | 2.89E-06 | .035 | .864 | ||
|
| |||||
| FA | Constant | 1.05 | |||
| Fiber Size | −2.10E-01 | −.841 | .707 | ||
|
| |||||
| Permeability | −2.17E-01 | −.313 | .806 | ||
|
| |||||
| Fibrosis | −2.15E-03 | −.031 | .807 | ||
|
| |||||
| Multi-Echo (Long T2) | |||||
| λ1 | Constant | 2.11E-03 | |||
| Permeability | 2.89E-05 | .362 | .131 | ||
|
| |||||
| Fibrosis | −2.26E-06 | −.286 | .213 | ||
|
| |||||
| Fiber Size | 4.36E-06 | .152 | .236 | ||
|
| |||||
| Edema | 1.82E-07 | .115 | .249 | ||
|
| |||||
| λ2 | Constant | 1.24E-03 | |||
| Permeability | 8.35E-04 | .821 | .673 | ||
|
| |||||
| Fibrosis | 3.86E-05 | .384 | .821 | ||
|
| |||||
| Fiber Size | −7.63E-05 | −.209 | .865 | ||
|
| |||||
| λ3 | Constant | −2.82E-04 | |||
| Fiber Size | 3.91E-04 | .870 | .756 | ||
|
| |||||
| Permeability | 4.07E-04 | .325 | .862 | ||
|
| |||||
| Fibrosis | 4.54E-06 | .037 | .864 | ||
|
| |||||
| MD | Constant | 1.55E-03 | |||
| Permeability | 5.66E-04 | .818 | .669 | ||
|
| |||||
| Fibrosis | 2.52E-05 | .368 | .805 | ||
|
| |||||
| Fiber Size | −6.03E-05 | −.243 | .863 | ||
|
| |||||
| FA | Constant | 3.07E-01 | |||
| Permeability | −3.27E-01 | −.784 | .615 | ||
|
| |||||
| Fibrosis | −1.74E-02 | −.421 | .792 | ||
|
| |||||
| Fiber Size | 4.12E-02 | .275 | .867 | ||