Table 1.

Characteristics of study participants

Variable	Mean (SD) or N (percent)
Age at death	89.7 (6.5)
Education	16.1 (3.6)
Female	745 (69.1%)
Baseline global cognition	−0.10 (0.62)
Global cognition proximate to death	−0.84 (1.11)
Final clinical diagnosis
No cognitive impairment	324 (30.5%)
Mild cognitive impairment	261 (24.6%)
AD dementia	459 (33.2%)
Other dementia	18 (1.7%)
Pathologic AD (Reagan criteria)	704 (65.3%)
Gross infarcts	388 (36.0%)
Cerebral amyloid angiopathy
None	229 (21.2%)
Mild	464 (43.0%)
Moderate	250 (23.2%)
Severe	136 (12.6%)
TDP 43
None	496 (46.0%)
Inclusions in amygdala	206 (19.1%)
Inclusions in amygdala and limbic regions	218 (20.2%)
Inclusions in amygdala, limbic and neocortical regions	159 (14.7%)
Atherosclerosis
None	217 (20.1%)
Mild	504 (46.7%)
Moderate	278 (25.8%)
Severe	80 (7.4%)
Arteriolosclerosis
None	312 (28.9%)
Mild	429 (39.8%)
Moderate	253 (23.4%)
Severe	85 (7.9%)
Microscopic infarcts	324 (30.0%)
Cortical Lewy bodies	143 (13.3%)
Hippocampal sclerosis	112 (10.4%)