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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Magn Reson Med. 2017 Dec 1;80(1):294–303. doi: 10.1002/mrm.27015

Figure 7.

Figure 7

(Left) Peripheral venous blood gas saturation measurements were higher in the subjects with SCD compared to control, most similar to the cerebral Yv predictions made by the HbS T2b model. (Right) Peripheral venous blood had the strongest correlation coefficient (r2=0.30) to cerebral Yv TRUST estimates when the HbS model was used in the SCD subjects. This relationship was no longer significant once oxygen content was accounted for in multivariate analysis, suggesting anemia and/or hyperemia is driving similar physiology in both vascular beds.