Table 2.

Apparent permeability factors (P_{e, 2h}) across the BeWo or HPEC monolayer and the co-culture.

Substance/NP	Cell layer	Static	Shaken
		Pe ×10−6 [cm s−1]a	Pe × 10−6 [cm s−1]a
Na-F	BeWo	0.0 ± 0.0	2.65 ± 0.5
	HPEC	9.0 ± 0.3	10.2 ± 0.4
	Co-culture	n.t.	1.1 ± 1.1
FITC-dextran	BeWo	n.t.	n.t.
	HPEC	n.t.	n.t.
	Co-culture	n.t.	n.t.
Antiyprine	BeWo	112.1 ± 54.1	106.4 ± 8.2
	HPEC	83.6 ± 6.5	76.5 ± 7.0
	Co-culture	400.2 ± 63.5	27.1 ± 10.7
Indomethacin	BeWo	39.5 ± 8.0	37.2 ± 11.9
	HPEC	19.0 ± 0.1	22.7 ± 0.4
	Co-culture	26.7 ± 0.2	30.7 ± 1.2
49 nm PS NPs	BeWo	0.0 ± 0.0	n.t.
	HPEC	0.5 ± 0.3	n.t.
	Co-culture	0.0 ± 0.0	0.0 ± 0.0
70 nm PS NPs	BeWo	n.t.	n.t.
	HPEC	n.t.	n.t.
	Co-culture	n.t.	n.t.

^aData represented as median ± mad (median absolute deviation) of 3–4 biologically independent experiments with 1 technical replicate each (n.t.: no translocation detected).