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Degree of insulitis is not reduced in infiltrated β2Ma or β2Mb transgenic mice. The mean scores of female β2M+/− (n = 8), β2M−/− (n = 7), β2Ma β2M−/− (n = 6), and β2Mb β2M−/− (n = 9, mice with infiltrate only) NOD mice are shown. Black bars, 0; diagonal stripes, 1; vertical stripes, 2; gray, 3; and hatched, 4. The proportion of islets exhibiting each level of insulitis severity was not significantly different between β2Ma, β2Mb, and β2M+/− mice.
