Table 1.

FAZ Dimension Data for all groups (first three columns) and Kruskal-Wallis Results for FAZ Data (last three columns). P-values of less than 0.0001, the statistical limit of our testing, are represented as <0.0001.

Descriptor	Healthy	DM	MDR	Healthy vs. DM*	Healthy vs. MDR*	DM vs. MDR*
Area (mm2)	0.196 ± 0.052	0.218 ± 0.063	0.257 ± 0.051	0.22	0.0004 (<)	0.0025 (<)
Perimeter (mm)	2.02 ± 0.247	2.17 ± 0.373	2.52 ± 0.381	0.13	‡0.0001 (<)	‡0.0001 (<)
Circumference (mm)	0.605 ± 0.127	0.585 ± 0.108	0.523 ± 0.122	0.64	0.03 (>)	0.017 (>)
Max. Diameter (mm)	0.578 ± 0.070	0.621 ± 0.089	0.669 ± 0.063	0.050 (<)	‡0.0001 (<)	0.0054 (<)
Min. Diameter (mm)	0.485 ± 0.072	0.509 ± 0.082	0.563 ± 0.058	0.26	0.0003 (<)	0.0007 (<)
Roundness+	0.872 ± 0.070	0.845 ± 0.082	0.886 ± 0.039	0.14	0.79	0.0417 (<)

⁺Roundness = defined by ImageJ – represents how closely region conforms to a circle.

^*If significant, a greater than or less than sign is presented to dictate which was greater, following the notation given in the group headings. For example, the FAZ area was bigger in the MDR group compared to the healthy control group (see first row and column #6 indicating the p-values for the Healthy vs. MDR).

^‡Indicates a P-value of less than 0.0001.