Table 1.
Demographic and clinical characteristics of patients, by time period and anatomical site
| Variable | Cases 2002–2008 (N = 1064) | Cases 2013–2015 | P | ||||
|---|---|---|---|---|---|---|---|
| Total cases N = 990 | Anterior N = 530 | Intermediate N = 74 | Panuveitis N = 226 | Posterior N = 160 | |||
| Median age at presentation years (IQR) | 40 (26–55) | 44 (29–57)* | 45 (32–59) | 26 (15–46) | 45 (30–58) | 42 (29–55) | <0.001 |
| Gender | 0.300 | ||||||
| Male | 481 (45) | 403 (41)* | 204 (38) | 36 (49) | 93 (41) | 70 (44) | |
| Female | 583 (55) | 587 (59) | 326 (62) | 38 (51) | 133 (59) | 90 (56) | |
| Site | <0.001 | ||||||
| Unilateral | 825 (78) | 499 (50)* | 364 (69) | 13 (18) | 57 (25) | 65 (41) | |
| Bilateral | 239 (22) | 491 (50) | 166 (31) | 61 (82) | 169 (75) | 95 (59) | |
| Granulomatous | <0.001 | ||||||
| Yes | 553 (52) | 545 (55) | 312 (59) | 13 (18) | 147 (65) | 73 (46) | |
| No | 511 (48) | 445 (45) | 218 (41) | 61 (82) | 79 (35) | 87 (54) | |
| Non-Italian ethnicity | 31 (3) | 106 (11)* | 43 (8) | 6 (8) | 44 (19) | 13 (8) | <0.001 |
| Has a specific diagnosis | 787 (74) | 759 (77) | 404 (76) | 45 (61) | 177 (78) | 133 (84) | 0.002 |
| Infectious etiology | 257 (24) | 301 (30)* | 173 (43) | 3 (7) | 68 (38) | 57 (43) | <0.001 |
| Systemic disease | na | 259 (26) | 114 (21) | 12 (16) | 110 (49) | 23 (14) | <0.001 |
* Indicates P value <0.05 for comparison between previous cases and current. Data are reported as median (interquartile range) or n (%)