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. 2018 Feb 26;15(5):6115–6122. doi: 10.3892/ol.2018.8117

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Copyright: © Zhao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Association of the miRNA expression patterns with several clinical features. (A) Tumors were characterized by pathological analysis as well, moderately or poorly differentiated. The expression of miR-143 and miR-145 was determined using RT-qPCR. U6 snRNA was used for miRNA normalization. Results are presented as the mean ± standard error of the mean. *P<0.05, **P<0.01, Student's t-test. The HBV-associated HCC samples were also grouped according to the following clinical features: (B) (+/-) Metastasis, (C) (+/-) cirrhosis or (D) (+/-) complete tumor capsule. No statistically significant association was identified between these clinical features and the expression of miR-143 and miR-145. miRNA/miR, microRNA; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; RT-qPCR, reverse transcription-quantitative polymerase chain reaction.