Skip to main content
. 2018 Feb 26;15(5):6115–6122. doi: 10.3892/ol.2018.8117

Figure 4.

Figure 4.

miR-143 and miR-145 serum levels are decreased in patients with HBV-associated HCC and may be used to predict tumorigenesis. RT-qPCR was used to determine the (A) miR-143 and (B) miR-145 expression levels in the serum samples. miR-143 and miR-145 expression was significantly decreased in the HBV-associated HCC samples compared with NC. Results are presented as the mean ± standard error of the mean. **P<0.01, Student's t-test. (C) The ROC curve of serum miR-143 expression for predicting HBV-associated HCC tumorigenesis. The AUC was calculated to be 0.813. (D) The ROC curve of serum miR-145 expression for predicting HBV-associated HCC tumorigenesis. The AUC was calculated to be 0.852. miRNA/miR, microRNA; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; ROC, receiver-operating characteristic; AUC, area under the ROC curve.