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. 2018 Feb 27;15(5):6666–6670. doi: 10.3892/ol.2018.8121

Figure 2.

Figure 2.

Figure 2.

LINE-1 methylation and UHRF1 expression comparision between 95 gastric cancer tissues and matched adjacent normal tissues. (A) LINE-1 methylation levels. The cancer tissues showed significantly lower levels of methylation than matched normal tissues (P<0.001 by Wilcoxon signed-rank test). (B) UHRF1 expression levels. UHRF1 mRNA expression levels were significantly higher in cancer tissues than matched normal tissues (P=0.001 by Wilcoxon signed-rank test). The mRNA levels were normalized to those of GAPDH. Horizontal lines represent the mean ± standard error of the mean as determined by triplicate assays. N, adjacent normal tissues; T, tumor tissues; LINE-1, long interspersed element-1; UHRF1, ubiquitin-like with PHD and ring-finger protein 1.