Figure 1.

Analysis of immune checkpoint molecules PD-1, LAG-3, TIM-3, and BTLA on CD4⁺ and CD8⁺ T cells in malignant ascites from ovarian cancer by multicolor flow cytometry. Various immune checkpoint molecules were expressed on both CD4⁺ and CD8⁺ T cells in ascites from EOC. FS, forward scatter; SS, side scatter; INT, integral; PD-1, programmed cell death protein-1; LAG-3, lymphocyte-activation gene-3; TIM-3, T-cell immunoglobulin and mucin-domain containing-3; BTLA, B and T lymphocyte attenuator.