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Serum anti-HBsAg response after delivery of yeast-derived rHBsAg with a mucosal adjuvant CT by gavage. Mice were gavaged with either 150 μg of rHBsAg + CT or PBS + CT at weeks 0 and 1, and all mice were boosted with 0.5 μg of alum-adsorbed rHBsAg at week 6. Circles, rHBsAg + CT; squares = PBS + CT.
