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Booster response seen by feeding HBsAg potatoes to mice. (A) Serum anti-HBsAg antibodies were measured in mice fed HB114–16 potatoes + CT at weeks 5, 6, and 7 after priming with a subimmunogenic dose of 0.5 μg of yeast-derived alum-adsorbed rHBsAg at week 0. (B) Nontransformed FL1607 potatoes + CT were fed to mice after priming at week 0 with 0.5 μg of yeast-derived alum-adsorbed rHBsAg. No antibodies were elicited.
