Figure 6.
Immunogenicity of unadjuvanted potatoes. Mice were fed HB114–16 transgenic potatoes alone without CT at weeks 0, 1, and 2, followed by a boost with a single injection of a subimmunogenic dose of yeast-derived alum-adsorbed rHBsAg at week 10. A very weak and transient primary response and a low level of secondary antibody response were generated in the absence of CT.