The identification of VEGF-specific antoantibody in sera in Western
blot analysis. Recombinant Xenopus VEGF, VEGF 120, 164,
188, and 165 as well as other growth factors (bFGF and PlGF) were
stained with sera isolated from mice immunized with XVEGF-p and other
control sera. The positive bands for VEGF can be recognized with the
sera isolated from mice immunized with XVEGF-p (A), but
negative staining from mice immunized with MVEGF-p (B)
or other control groups. (C) Positive staining for bFGF
and PlGF was found with the antibodies against bFGF and PlGF,
respectively, as positive controls for A, but
(D) negative staining was found with control IgG.