5-FU	5-fluorouracil
ADCC	antibody-dependent cellular cytotoxicity
AKT	protein kinase B
ATM	mutated in the disease ataxia telangiectasia
ATP	adenosine triphosphate
Apo2L	Apo-2 ligand
Bak	Bcl-2 antagonist or killer
Bax	Bcl-2-associated X protein
Bcl-2	B-cell CLL/lymphoma 2
Bcl-XL	B-cell lymphoma-extra-large
BH3	Bcl-2 homology domain 3
Bid	BH3-only protein
BITC	benzyl isothiocyanate
CDK9	cyclin-dependent kinase 9
c-FLIP	cellular (FADD-like IL-1β-converting enzyme)-inhibitory protein
cIAP	cellular IAP
c-Myc	avian myelocytomatosis virus oncogene cellular homolog
DcR	decoy receptor
CPT	circularly permuted TRAIL
DD	death domain
DDR	DNA damage response
DGCR8	DiGeorge critical region8
DR	death receptor
ER	endoplasmic reticulum
ERK	extracellular signal-regulated kinase
FADD	Fas-associated death domain
Fc	Fragment crystallizable
Flag	DYKDDDDK
FLICE	FADD-like IL-1β-converting enzyme
FOLFIRINOX	FOL-folinic acid, F-5-fluorouracil (5-FU), IRIN-irinotecan, OX-oxaliplatin
GALNT14	N-acetylgalactosaminyltransferase-14
GTP	guanosine-5′-triphosphate
HcAbs	heavy-chain-only antibodies
HDAC	histone deacetylase
HMGA2	high-mobility group AT-hook 2
IAP	inhibitor of apoptosis protein
IGF-R	insulin-like growth factor receptor
IgG	immunoglobulin
IGFR	insulin-like growth factor receptor
IKK	inhibitor of κB kinase
IMS	intermembrane space
IκB	inhibitor of κB
IZ	isoleucine zipper
JNK	c-JUN N-terminal kinase
KRAS	Kirsten rat sarcoma viral oncogene homolog
LUBAC	linear ubiquitin chain assembly complex
LZ	leucine zipper
mAb	monoclonal antibody
MAPK	mitogen-activated protein kinase
Mcl-1	myeloid leukemia cell differentiation protein
memTRAIL	membrane-bound TRAIL
miRNA	micro RNA
MOM	mitochondrial outer membrane
MOMP	mitochondrial outer membrane permeabilization
MTD	membrane-proximal domain
nab	nanoparticle albumin-bound
NEMO	NF-κB essential modifier
NF-κB	nuclear factor kappa light chain enhancer of activated B cells
N-glyc	N-glycosylation
NIK	NF-κB-inducing kinase
nTRAIL	nuclear TRAIL
O-glyc	O-glycosylation
OPG	osteoprotegerin
p38 MAPK	p38 mitogen-activated protein kinase
PARP	poly-ADP ribose polymerase
PCD	programmed cell death
PDAC	pancreatic ductal adenocarcinoma
Rac1	Ras-related C3 botulinum toxin substrate 1
RANKL	receptor activator of nuclear factor κB ligand
Ras	Rat sarcoma
rhTRAIL	recombinant human TRAIL
RIPK	receptor-interacting serine/threonine protein kinase 1
scTRAIL-RBD	single-chain-TRAIL-receptor-binding domain
Smac/DIABLO	second mitochondrial activator of caspases/direct inhibitor of apoptosis-binding protein with low pI
SR	superfamily
SRC	Rous sarcoma oncogene cellular homolog
STAT	signal transducer and activator of transcription
sTRAIL	soluble TRAIL
TNF	tumor necrosis factor
TAPE	threonine, alanine, proline, glutamine
TRAIL	TNF-related apoptosis-inducing ligand
TRAIL-R	Trail receptor
Ub	ubiquitin
VHH	heavy chain domain
XIAP	X-linked inhibitor of apoptosis protein