Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Mar 20;10(3):81. doi: 10.3390/cancers10030081

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The palmitate group (colored yellow) extends towards the interior of YBD shown as a grey surface representation. The lipid pockets of (A) TEAD2 and (B) TEAD3 are identical except for the Phe/Tyr difference, which is shown in blue stick format. For TEAD3, the bulkier Tyr233 requires the lipid chain to reorient relative to the TEAD2 structure. The most noticeable reorientations are marked with red arrows on the TEAD3 lipid pocket to illustrate the alkyl chain moving down and the carbonyl group rotating out towards the solvent.