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Ratio of 8-OH-dG/105 dG (pmol/pmol) in DNA obtained from skin of experimental and control mice after an 8-week treatment with either DMBA or DMBA/triterpenoid saponins/TPA. Skins were harvested on day 2 after last dosing of the test compounds in the multistage carcinogenesis experiment (DMBA/TPA). Asterisks indicate groups that are statistically different from pooled controls.
