Skip to main content
. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Pediatr Blood Cancer. 2017 Sep 17;65(2):10.1002/pbc.26825. doi: 10.1002/pbc.26825

Table 2.

Relative IC50 Values for cisplatin and melphalan in the presence and absence of M6620

Line rIC50 for Cisplatin rIC50 for Cisplatin + M6620 (75nM) Ratio rIC50 for Melphalan rIC50 for Melphalan + M6620 (75nM) Ratio
RD 1.84 μM 2.10 μM 0.88 5.34 μM 2.48 μM 2.15
Rh41 5.56 μM 3.48 μM 1.60 8.37 μM 2.32 μM 3.61
Rh18 1.22 μM 0.72 μM 1.70 15.59 μM 3.17 μM 4.92
Rh30 2.18 μM 0.97 μM 2.24 3.35 μM 2.22 μM 1.51
BT-12 0.73 μM 0.69 μM 1.05 3.37 μM 3.41 μM 0.99
CHLA-266 2.92 μM 3.44 μM 0.85 16.18 μM 3.69 μM 4.38
TC-71 1.52 μM 1.07 μM 1.42 11.29 μM 9.49 μM 1.19
CHLA-9 0.25 μM 0.28 μM 0.89 0.69 μM 0.52 μM 1.33
CHLA-10 1.39 μM 0.76 μM 1.83 3.23 μM 2.01 μM 1.61
CHLA-258 7.96 μM 9.64 μM 0.83 5.61 μM 1.72 μM 3.26
GBM2 0.74 μM 0.88 μM 0.84 4.53 μM 4.98 μM 0.91
NB-1643 0.75 μM 0.85 μM 0.88 1.19 μM 1.19 μM 1.00
NB-EBc1 1.55 μM 0.67 μM 2.31 4.29 μM 2.90 μM 1.48
CHLA-90 7.94 μM 5.16 μM 1.54 51.68 μM 12.79 μM 4.04
CHLA-136 5.25 μM 0.75 μM 6.99 3.16 μM 1.73 μM 1.83
NALM-6 1.44 μM 0.55 μM 2.62 1.73 μM 0.50 μM 3.46
COG-LL-317 1.37 μM 1.41 μM 0.97 0.73 μM 0.48 μM 1.53
RS4-11 0.89 μM 0.84 μM 1.06 2.19 μM 1.05 μM 2.07
MOLT-4 1.36 μM 0.09 μM 15.1 1.13 μM 1.24 μM 0.91
CCRF-CEM 2.33 μM 2.55 μM 0.91 3.49 μM 0.91 μM 3.82
CCRF-CEM-2 1.76 μM 1.31 μM 1.34 3.20 μM 1.29 μM 2.48
KASUMI-1 2.93 μM 1.09 μM 2.69 5.53 μM 0.73 μM 7.55
KARPAS-299 0.50 μM 0.30 μM 1.67 3.43 μM 0.72 μM 4.79
RAMOS 3.40 μM 1.82 μM 1.87 3.65 μM 3.95 μM 0.92
Median 1.53 μM 0.92 μM 1.48 3.46 μM 1.87 μM 1.95