Table 2.
Line | rIC50 for Cisplatin | rIC50 for Cisplatin + M6620 (75nM) | Ratio | rIC50 for Melphalan | rIC50 for Melphalan + M6620 (75nM) | Ratio |
---|---|---|---|---|---|---|
RD | 1.84 μM | 2.10 μM | 0.88 | 5.34 μM | 2.48 μM | 2.15 |
Rh41 | 5.56 μM | 3.48 μM | 1.60 | 8.37 μM | 2.32 μM | 3.61 |
Rh18 | 1.22 μM | 0.72 μM | 1.70 | 15.59 μM | 3.17 μM | 4.92 |
Rh30 | 2.18 μM | 0.97 μM | 2.24 | 3.35 μM | 2.22 μM | 1.51 |
BT-12 | 0.73 μM | 0.69 μM | 1.05 | 3.37 μM | 3.41 μM | 0.99 |
CHLA-266 | 2.92 μM | 3.44 μM | 0.85 | 16.18 μM | 3.69 μM | 4.38 |
TC-71 | 1.52 μM | 1.07 μM | 1.42 | 11.29 μM | 9.49 μM | 1.19 |
CHLA-9 | 0.25 μM | 0.28 μM | 0.89 | 0.69 μM | 0.52 μM | 1.33 |
CHLA-10 | 1.39 μM | 0.76 μM | 1.83 | 3.23 μM | 2.01 μM | 1.61 |
CHLA-258 | 7.96 μM | 9.64 μM | 0.83 | 5.61 μM | 1.72 μM | 3.26 |
GBM2 | 0.74 μM | 0.88 μM | 0.84 | 4.53 μM | 4.98 μM | 0.91 |
NB-1643 | 0.75 μM | 0.85 μM | 0.88 | 1.19 μM | 1.19 μM | 1.00 |
NB-EBc1 | 1.55 μM | 0.67 μM | 2.31 | 4.29 μM | 2.90 μM | 1.48 |
CHLA-90 | 7.94 μM | 5.16 μM | 1.54 | 51.68 μM | 12.79 μM | 4.04 |
CHLA-136 | 5.25 μM | 0.75 μM | 6.99 | 3.16 μM | 1.73 μM | 1.83 |
NALM-6 | 1.44 μM | 0.55 μM | 2.62 | 1.73 μM | 0.50 μM | 3.46 |
COG-LL-317 | 1.37 μM | 1.41 μM | 0.97 | 0.73 μM | 0.48 μM | 1.53 |
RS4-11 | 0.89 μM | 0.84 μM | 1.06 | 2.19 μM | 1.05 μM | 2.07 |
MOLT-4 | 1.36 μM | 0.09 μM | 15.1 | 1.13 μM | 1.24 μM | 0.91 |
CCRF-CEM | 2.33 μM | 2.55 μM | 0.91 | 3.49 μM | 0.91 μM | 3.82 |
CCRF-CEM-2 | 1.76 μM | 1.31 μM | 1.34 | 3.20 μM | 1.29 μM | 2.48 |
KASUMI-1 | 2.93 μM | 1.09 μM | 2.69 | 5.53 μM | 0.73 μM | 7.55 |
KARPAS-299 | 0.50 μM | 0.30 μM | 1.67 | 3.43 μM | 0.72 μM | 4.79 |
RAMOS | 3.40 μM | 1.82 μM | 1.87 | 3.65 μM | 3.95 μM | 0.92 |
Median | 1.53 μM | 0.92 μM | 1.48 | 3.46 μM | 1.87 μM | 1.95 |