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. 2018 Mar 7;12(1 Suppl):110–115. doi: 10.2101/Ajid.12v1S.16

Table 3.

In vivo inhibition of mice infected-P. berghei treated with ethanol extract of Cassia spectabilis leaves at single dose(150 mg/kg body weight) and multiple dose (2 x150 mg/kg body weight and 3 x 150 mg/kg body weight) during 4 days

Sample mg/kg bodyweight Rep D0 D4 Percentage of growth Average of percentage growth percentage inhibition Average of percentage inhibition
Negative control 1 1.25 8.28 7.03 7.03± 1.18 - -
2 0.55 10.07 9.52 -
3 2.48 8.84 6.36 -
4 1.29 8.32 7.03 -
5 0.77 7.01 6.24 -
6 1.28 7.28 6.00 -

150 1 2.17 6.37 4.20 3.78± 0.27 40.26 46.25±3.83
2 1.40 5.35 3.95 43.81
3 1.32 5.17 3.85 45.23
4 2.25 5.68 3.43 51.21
5 1.75 5.53 3.78 46.23
6 1.62 5.08 3.46 50.78

2x 150 1 3.12 5.57 2.45 3.33± 0.50 65.15 52.58± 7.18
2 1.54 4.81 3.27 53.49
3 0.94 5.13 4.19 40.10
4 1.91 5.22 3.31 52.92
5 1.61 5.04 3.43 51.21
6 1.83 5.16 3.33 52.63

3x150 1 1.94 5.10 3.16 2,64± 0.29 55.05 62.42±1,62
2 1.66 4.50 2.66 62.16
3 1.73 4.36 2.63 62.59
4 0.99 3.58 2.59 63.16
5 1.62 4.42 2.62 62.73
6 1.89 4.08 2.19 68.85