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AJCC indicates American Joint Committee on Cancer Staging Manual; BWH, Brigham and Women’s Hospital.
aHigh-risk factors: tumor thickness >2 mm, Clark level IV/V, poor or undifferentiated, perineural invasion, localization at ear or lip.
bHigh-risk factors: Tumor diameter ≥2 cm, invasion beyond subcutaneous fat, poorly differentiated, and perineural invasion.
