Table 2. Patients With Cutaneous Squamous Cell Carcinoma With and Without Metastasis Within 5 Years of Individual Follow-up, Staged According to 4 Staging Systems.
| Staging System | No. (%) | χ2 Test P Value |
|
|---|---|---|---|
| With Metastasis (n = 103) |
Without Metastasis (n = 81) |
||
| AJCC, Seventh Edition | .003 | ||
| T1 | 14 (14.4) | 27 (33.3) | |
| T2 | 83 (85.6) | 54 (66.7) | |
| T3 | 0 | 0 | |
| T4 | 0 | 0 | |
| Unknown | 6 (5.8) | 0 | |
| Breuninger et al | <.001 | ||
| Diameter | |||
| Low-risk (≤2 cm) | 55 (53.4) | 74 (91.4) | |
| High-risk (>2 cm) | 40 (38.8) | 7 (8.6) | |
| Unspecified | 8 (7.8) | 0 | |
| Depth of invasion | |||
| No risk (<2 mm) | 7 (6.8) | 24 (29.6) | |
| Low-risk (2-6 mm) | 48 (46.6) | 50 (61.7) | |
| High-risk (>6 mm) | 34 (33.0) | 6 (7.4) | |
| Unspecified | 14 (13.6) | 1 (1.2) | |
| With additional factors | |||
| Low-risk | 49 (47.6) | 61 (75.3) | |
| High-risk | 54 (52.4) | 20 (24.7) | |
| BWH | <.001 | ||
| T1 | 32 (31.1) | 62 (76.5) | |
| T2a | 38 (36.9) | 16 (19.8) | |
| T2b | 33 (32.0) | 3 (3.7) | |
| T3 | 0 | 0 | |
| AJCC, Eighth Edition | <.001 | ||
| T1 | 26 (32.9) | 39 (69.6) | |
| T2 | 8 (10.1) | 6 (10.7) | |
| T3 | 45 (57.0) | 11 (19.7) | |
| T4 | 0 | 0 | |
| Unknown | 5 (4.9) | 0 | |
Abbreviations: AJCC, American Joint Committee on Cancer Staging Manual; BWH, Brigham and Women’s Hospital.