Table 3. External Validation of 4 Staging Systems for Cutaneous Squamous Cell Carcinoma Presented as Discrimination and Calibration Statistics.
| Staging System | No. | Sensitivity, % | Specificity, % | Correctly Classified % | C Index | R2 |
|---|---|---|---|---|---|---|
| AJCC, Seventh Edition | 178 | 85.6 | 33.3 | 61.8 | 0.59 | 0.04 |
| Breuninger et al | 168 | 77.3 | 75.0 | 76.2 | 0.81 | 0.23 |
| BWH | 184 | 68.9 | 76.5 | 72.3 | 0.75 | 0.18 |
| AJCC, Eighth Editiona | 135 | 67.1 | 69.6 | 68.2 | 0.70 | 0.12 |
Abbreviations: AJCC, American Joint Committee on Cancer Staging Manual; BWH, Brigham and Women’s Hospital.
a
Head and neck tumors only.
b
Sensitivity, specificity, correctly classified, concordance index (C index), and Nagelkerke R2.