Table 1. Incidence of Early and Advanced Age-Related Macular Degeneration (AMD) per Person According to Sex and Age Groups in the ALIENOR Study, 2006-2012.
| Characteristic | No. | 5-y Risk, % | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sex Group | Age Group | Total | ||||||||||||||
| Men | Women | 73-79 y | ≥80 y | |||||||||||||
| Total PYs | Cases | Incidence per 1000 PYs (95% CI) | Total PYs | Cases | Incidence per 1000 PYs (95% CI) | Total PYs | Cases | Incidence per 1000 PYs (95% CI) | Total PYs | Cases | Incidence per 1000 PYs (95% CI) | Total PYs | Cases | Incidence per 1000 PYs (95% CI) | ||
| Advanced AMD | 911 | 13 | 14.3 (8.3-24.6) | 1506 | 32 | 21.2 (15.0-30.0) | 1072 | 13 | 12.1 (7.0-20.9) | 1345 | 32 | 23.8 (16.8-33.6) | 2417 | 45 | 18.6 (13.9-24.9) | 8.9 |
| Neovascular AMD | 934 | 2 | 2.1 (0.5-8.6) | 1531 | 20 | 13.1 (8.4-20.3) | 1078 | 9 | 8.3 (4.3-16.0) | 1387 | 13 | 9.4 (5.4-16.1) | 2465 | 22 | 8.9 (5.9-13.6) | 4.4 |
| Atrophic AMD | 911 | 11 | 12.1 (6.7-21.8) | 1506 | 13 | 8.6 (5.0-14.9) | 1072 | 4 | 3.7 (1.4-9.9) | 1345 | 20 | 14.9 (9.6-23.0) | 2417 | 24 | 9.9 (6.7-14.8) | 4.8 |
| Early AMD | 615 | 42 | 68.3 (50.5-92.4) | 888 | 78 | 87.8 (70.4-109.7) | 745 | 49 | 65.8 (49.7-87.0) | 758 | 71 | 93.7 (74.2-118.2) | 1503 | 120 | 79.9 (66.8-95.5) | 32.9 |
| Distinct soft drusen | 773 | 35 | 45.3 (32.5-63.0) | 1191 | 76 | 63.8 (51.0-79.9) | 925 | 44 | 47.6 (35.4-63.9) | 1039 | 67 | 64.5 (50.7-81.9) | 1964 | 111 | 56.5 (46.9-68.1) | 24.6 |
| Indistinct soft drusen | 807 | 28 | 34.7 (23.9-50.2) | 1257 | 44 | 35.0 (26.1-47.0) | 953 | 35 | 36.7 (26.4-51.2) | 1112 | 37 | 33.3 (24.1-45.9) | 2064 | 72 | 34.9 (27.7-43.9) | 16.0 |
| Reticular pseudodrusen | 882 | 9 | 10.2 (5.3-19.6) | 1414 | 25 | 17.7 (11.9-26.2) | 1043 | 8 | 7.7 (3.8-15.3) | 1253 | 26 | 20.8 (14.1-30.5) | 2296 | 34 | 14.8 (10.6-20.7) | 7.1 |
| Large area of soft drusen | 807 | 16 | 19.8 (12.2-32.4) | 1178 | 32 | 27.2 (19.2-38.4) | 928 | 18 | 19.4 (12.2-30.8) | 1057 | 30 | 28.4 (19.9-40.6) | 1985 | 48 | 24.2 (18.2-32.1) | 11.4 |
| Intermediate soft drusen | 316 | 66 | 209.2 (164.4-266.3) | 368 | 90 | 244.3 (198.7-300.3) | 386 | 84 | 217.5 (175.6-269.3) | 298 | 72 | 241.9 (192.0-304.7) | 684 | 156 | 228.1 (195.0-266.9) | 68.0 |
| Pigmentary abnormalities | 565 | 31 | 54.9 (38.6-78.1) | 899 | 69 | 76.7 (60.6-97.1) | 708 | 32 | 45.2 (32.0-63.9) | 756 | 68 | 89.9 (70.9-114.0) | 1464 | 100 | 68.3 (56.1-83.1) | 28.9 |
Abbreviation: PY, person-year.