Table 3.
Relative excess risk due to interaction (RERI) between air pollution and ACEs on CVD-related outcomes a,b.
| Outcome | PM2.5 and ACEs | PM10 and ACEs | NO2 and ACEs | |||
|---|---|---|---|---|---|---|
| Diabetes | 0.02 | (−0.22, 0.25) | 0.26 | (0.05, 0.48) * | 0.09 | (−0.13, 0.30) |
| Stroke | 0.02 | (−0.40, 0.44) | −0.06 | (−0.44, 0.31) | 0.14 | (−0.27, 0.55) |
| MI | −0.10 | (−0.44, 0.24) | −0.02 | (−0.33, 0.30) | −0.10 | (−0.44, 0.25) |
| Obesity | −0.03 | (−0.18, 0.13) | −0.08 | (−0.23, 0.07) | −0.01 | (−0.16, 0.14) |
a PM2.5: fine particulate matter, PM10: particulate matter less than 10 µm in diameter, NO2: nitrogen dioxide, ACEs: adverse childhood experiences, MI: myocardial infarction. b RERIOR (relative excess risk due to interaction) is calculated as (OR11) − (OR10) − (OR01) + 1 where subscript 11 designates high air pollution and high ACEs, subscript 10 designates the group with high air pollution and low ACEs, and subscript 01 designates the group with low air pollution and high ACEs. Models are adjusted for age, race, sex, education, employment, income, urban versus rural zip code and neighborhood deprivation index (NDI). Estimates with a p-value < 0.05 are indicated with an asterisk.