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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Hypertension. 2018 Jan 8;71(3):457–464. doi: 10.1161/HYPERTENSIONAHA.117.10527

Table 5.

Best fitting models of the bivariate SEM analysis

Probe ID Trait 1 Trait 2 Best Model rg re Standardized rg Standardized re
ILMN_2413508 CD97 SBP a21≠0 0.39(0.18,0.59) -- 1.00 --
ILMN_2413508 CD97 DBP a21≠0 0.34(0.12,0.56) -- 1.00 --
ILMN_1656920 CRIP1 SBP a21≠0 | e21≠0 * 0.22(−0.26,0.98) 0.06(−0.11,0.23) 0.77 0.23
ILMN_1656920 CRIP1 DBP a21≠0 | e21≠0 * 0.28(0.00,0.54) 0.05(−0.11,0.22) 0.80 0.20
ILMN_1671766 F12 SBP a21≠0 | e21≠0 * 0.015(−0.09,0.40) 0.07(−0.10,0.24) 0.69 0.31
ILMN_1696749 LMNA SBP e21≠0 -- 0.24(0.09, 0.37) -- 1.00
ILMN_1696749 LMNA DBP e21≠0 -- 0.28(0.14,0.41) -- 1.00
ILMN_1745282 MOK SBP a21≠0 & e21≠0 0.27(0.01,0.49) 0.26(0.09,0.41) 0.52 0.48
ILMN_2046730 S100A10 DBP a21≠0 | e21≠0 * 0.14(−0.20,0.45) 0.07(−0.10,0.24) 0.56 0.44
ILMN_1758938 SLC31A2 SBP e21≠0 -- 0.27(0.14,0.39) -- 1.00
ILMN_1758938 SLC31A2 DBP e21≠0 -- 0.17(0.03,0.30) -- 1.00
ILMN_1676408 TAGAP SBP a21≠0 | e21≠0 * 0.08(−1.00,1.00) 0.17(−0.01,0.33) 0.36 0.64
ILMN_2090105 TAGLN2 SBP e21≠0 -- 0.29(0.15,0.41) -- 1.00
ILMN_1765578 TIPARP SBP a21≠0 0.46(0.20,0.67) -- 1.00 --
ILMN_1765578 TIPARP DBP a21≠0 0.40(0.18,0.66) -- 1.00 --
ILMN_1797744 TPPP3 SBP a21≠0 0.41(0.18,0.65) -- 1.00 --
ILMN_1797744 TPPP3 DBP a21≠0 0.45(0.21,0.69) -- 1.00 --
ILMN_2276952 TSC22D3 SBP e21≠0 -- 0.22(0.09,0.34) -- 1.00
ILMN_2276952 TSC22D3 DBP e21≠0 -- 0.21(0.08,0.33) -- 1.00
*

a21 and e21 cannot be set to 0 at the same time

rg is genetic correlation.( rg=a11a21/a112(a112+a222)) -- indicates that it can be set to 0 in the best fitting model.

re is nonshared-environmental correlation.( rg=e11e21/e112(e112+e222))--indicates that it can be set to 0 in the best fitting model.

Standardized rg = a11*a21/rp, standardized re = e11*e21/rp, where rp= a11*a21 + c11*c21 + e11*e21