. Author manuscript; available in PMC: 2019 Apr 1.

Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2018 Feb 8;57(4):235–244.e2. doi: 10.1016/j.jaac.2018.01.015

TABLE 3.

Differences in Antidepressant Response in Children and Adolescents with Generalized, Separation and/or Social Anxiety Disorders for Antidepressant Class and Selective Serotonin Reuptake Inhibitor (SSRI) Dose.

	Difference in Response for SSRIs and SSNRI Treatment			Difference in Response High and Low Dose SSRI Treatment
Time (week)	δ	95% Credible Interval	Significance (vs. baseline)	δ	95% Credible Interval	Significance (vs. baseline)
0	0.003	−0.031, 0.038	p=0.681	0.018	−0.017, 0.203	p=0.648
4	−0.078	−0.112, −0.044	p=0.009	−0.014	−0.199, 0.170	p=0.381
8	−0.125	−0.160, −0.091	p=0.004	−0.033	−0.218, 0.152	p=0.249
12	−0.159	−0.194, −0.125	p<0.0028	−0.046	−0.304, 0.139	p=0.180

Note: Negative values reflect improvement. SSRI = selective serotonin reuptake inhibitor; SSNRI = selective serotonin norepinephrine reuptake inhibitor; δ = standardized medication-placebo difference.