Table 1.

Patient characteristics

Case	Age/sex	Course	Disease duration	Last flare‐up	Neurological disability	MFIS total	TICS score	Lesion burden
1	59/F	RR	15	054	05	23	26	46,243.90
2	55/F	RR	14	012	32	73	24	2,707.11
3	46/F	RR	11	002	21	78	26	20,758.90
4	55/F	RR	20	001	36	44	28	14,816.00
5	49/F	RR	06	067	12	39	26	2,789.85
6	43/F	SP	04	010	07	17	25	677.03
7	48/F	RR	07	007	04	07	32	475.23
8	28/M	RR	05	016	06	24	26	13,272.20
9	63/F	RR	09	108	10	44	31	7,469.53
10	55/F	RR	08	009	24	42	26	1,751.60

Disease duration in years. Last flare‐up (i.e., exacerbation) in months. Neurological disability based upon total self‐reported neurological disability [Verdier‐Taillefer et al., 1994].

RR, relapsing‐remitting; SP, secondary progressive; MFIS total, Modified Fatigue Impact Scale total score [Fisk et al., 1994]. TICS, Telephone Interview for Cognitive Status score [Brandt et al., 1988]. Lesion burden, total white matter lesion burden in mm³.