Table 1. Demographic and clinical characteristics of study population.
Shows the different demographic and clinical characteristics between patients with DN, patients with NDRD and patients with NDRD + DN.
| DN n = 717 | NDRD n = 788 | NDRD + DN n = 99 | P value | |
|---|---|---|---|---|
| Age | 50.24 ± 10.87 | 52.11 ± 11.89a | 53.82 ± 10.00b | 0.001 |
| Male sex | 433 (60.39%) | 434 (55.08%)a | 65 (65.66%)c | 0.033 |
| SCr | 145.37 ± 111.72 | 103.40 ± 102.80a | 171.28 ± 169.88c | <0.001 |
| eGFR | 62.21 ± 33.20 | 83.56 ± 31.96a | 61.83 ± 35.85c | <0.001 |
| Clinical indication | ||||
| NS | 371 (51.7%) | 398 (50.5%) | 55 (55.6%) | 0.616 |
| AKI | 2 (0.3%) | 24 (3.0%)a | 5 (5.1%)b | <0.001 |
| CPKI | 105 (14.6%) | 50 (6.3%)a | 14 (14.1%)c | <0.001 |
| Proteinuria + hematuria | 97 (13.5%) | 151 (19.2%)a | 10 (10.1%)b,c | 0.003 |
| Proteinuria | 141 (19.7%) | 155 (19.7%) | 15 (15.2%) | 0.553 |
| Hematuria | 1 (0.1%) | 10 (1.3%)a | 0b,c | 0.024 |
| Time duration | ||||
| 2004–2007 | 20 | 15 | 0 | |
| 2008–2011 | 108 | 141 | 11 | |
| 2012–2014 | 589 | 632 | 88 |
Notes.
Quantitative data was expressed as mean ± standard deviation (SD), categorical data was presented as frequencies and percentages (n(%)). Differences between categorical data were analyzed by χ2 test; differences between quantitative data were analyzed by analysis of variance(ANOVA).
- SCr
- serum creatinine
- eGFR
- estimated glomerular filtration rate
- T1DM
- type 1 diabetes mellitus
- NS
- nephrotic syndrome
- AKI
- acute kidney injury
- CKD
- chronic kidney disease
- DN
- diabetic nephropahty
- NDRD
- non-diabetic renal disease
a
P < 0.05 for comparison of NDRD versus DN groups.
b
P < 0.05 for comparison of NDRD + DN versus DN groups.
c
P < 0.05 for comparison of NDRD + DN versus NDRD groups.