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. Author manuscript; available in PMC: 2018 Mar 30.
Published in final edited form as: Wiley Interdiscip Rev Dev Biol. 2016 Sep 1;6(1):10.1002/wdev.245. doi: 10.1002/wdev.245

FIGURE 2.

FIGURE 2

Skeletal joints in zebrafish and mouse. (a) In zebrafish fry at 5 days postfertilization, well-studied cartilaginous joints (arrows) include the jaw joint between Meckel’s and palatoquadrate cartilages and the bipartite hyoid joint between hyosymplectic, interhyal, and ceratohyal cartilages. (b) In a mouse embryo at E17.5, representative joints include the shoulder and elbow joints (arrows) and interphalangeal joints (arrowheads). As in young zebrafish, these joints are largely cartilaginous at this stage. (c) The adult zebrafish skeleton is largely composed of bone and contains many types of joints (arrows), including sutures in the skull, intervertebral joints, and synovial joints in the jaw and pectoral fin. (d) The mouse skeleton at postnatal Day 21 has similar joints to zebrafish, including sutures, intervertebral discs, and synovial joints in the knee and digits (i.e., interphalangeal). Skeletons were stained with alcian blue for cartilage and alizarin red for bone. ch, ceratohyal; dr, distal radial; fe, femur; hs, hyosymplectic; ih, interhyal; M, Meckel’s; pq, palatoquadrate; pr, proximal radial; t, tibia.