Table S4.
Comparison of parameters between groups according to valid data (n=725)
| Tested parameter | Without 6-MWT and ABG (n=133) | Only with 6-MWT (n=201) | Only with ABG (n=40) | With 6-MWT and ABG (n=351) | p-value |
|---|---|---|---|---|---|
| Demography | |||||
| Sex – men | 97 (72.9%) | 146 (72.6%) | 25 (62.5%) | 252 (71.8%) | 0.597 |
| Age at inclusion | 67.4 (10.3) | 65.3 (10.0) | 69.4 (9.3) | 67.0 (8.5) | 0.078 |
| BMI | 26.7 (5.6) | 27.1 (5.4) | 25.9 (4.7) | 26.9 (6.1) | 0.553 |
| Symptoms | |||||
| mMRC | 2.0 (1.1) | 2.3 (0.9) | 2.5 (1.1) | 2.2 (1.2) | 0.007 |
| CAT | 17.3 (8.2) | 15.5 (7.2) | 17.5 (8.0) | 15.5 (7.9) | 0.067 |
| Exacerbations | |||||
| Treated at home (moderate) | 0.6 (1.1) | 0.8 (1.2) | 0.9 (1.1) | 0.9 (1.5) | 0.223 |
| Requiring hospitalization (severe) | 0.2 (0.6) | 0.2 (0.5) | 0.7 (0.8) | 0.5 (0.9) | <0.001 |
| Total | 0.8 (1.4) | 1.0 (1.4) | 1.6 (1.4) | 1.4 (1.9) | <0.001 |
| Lung function | |||||
| FEV1 (%) | 45.3 (11.2) | 47.7 (11.6) | 44.8 (12.9) | 43.2 (11.4) | <0.001 |
| FVC (%) | 71.8 (16.8) | 69.1 (15.2) | 71.3 (15.5) | 68.0 (19.5) | 0.057 |
| TLCO (% pred) | 52.1 (21.9) | 62.1 (24.1) | 48.6 (16.2) | 49.4 (21.0) | <0.001 |
Notes:
Categorical parameters are described by absolute (relative) frequency. Differences are tested by Fisher’s exact test. Continuous parameters are described by mean (SD). Differences are tested by Kruskal–Wallis test. Significant differences are indicated in bold.
Abbreviations: 6-MWT, 6-minute walking test; ABG, arterial blood gas; BMI, body mass index; CAT, COPD Assessment Test; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; mMRC, modified Medical Research Council dyspnea scale; pred, predicted value; TLco, transfer factor for carbon monoxide.