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. 2018 Mar 23;9:156. doi: 10.3389/fneur.2018.00156

Table 2.

Synopsis of the main diagnostic criteria proposed for Parkinson’s disease, in terms of methodology, size, and relative diffusion.

Reference Year of publication Diagnostic features Size (no. of pages) Diffusion
James Parkinsona (1) 1817 Clinical 66 +++
Gibb and Leesb (10) (UKPDSBB) 1988 Clinical 44 +++
Calne et al.a (11) 1992 Clinical 3 +
Larsen et al.a (12) 1994 Clinical 10 +
Gelb et al.a (13) 1999 Clinical 7 ++
EFNS/MDS-ESc (18) 2013 Clinical and laboratory 19 ++
MDSa (21, 41) 2015 Clinical and laboratory 9 +++(?)

Type of study: asingle- or multi-expert opinion; bSingle center clinicopathological study; cSystematic review.

EFNS/MDS-ES, European Federation of Neurological Societies/Movement Disorders Society-European Section; UKPDSBB, United Kingdom Parkinson’s disease society brain bank clinical diagnostic criteria; MDS, Movement Disorder Society.