. 2018 Feb 28;19(3):694. doi: 10.3390/ijms19030694

Table 5.

Potential factors influencing the heterogeneity in the responses to the supplementation with ellagitannins and/or anthocyanins-containing products investigated in this meta-analysis.

Factors
Baseline BMI	25.0 ^a (normal and (or) underweight)			≥25.0 (overweight and (or) obese)
Sex	Women			Men
Smoking	Non-smokers			Smokers
Country where the study was conducted	East Asian countries (Japan, Korea, China)	All-other- countries-but-not-East Asian	North America (USA, Canada)	European countries
Country where the study was conducted	East Asian countries (Japan, Korea, China)	All-other- countries-but-not-East Asian	North America (USA, Canada)	Non-Mediterranean countries (Denmark, Norway, Finland, The Netherlands, Germany, Poland, UK, Scotland, France, Czech Republic)	Mediterranean countries (Italy, Spain, Greece)
Medication	Yes			No
Health status	Healthy individuals ^b		Individuals ‘at a risk‘ of disease ^c		Individuals with a reported disease ^d
Main source of compounds	Ellagitannins			Anthocyannins
Main source of compounds	Pomegranate		Nuts	Berries	Red wine and red grapes
Diet during intervention	Controlled diet (specifically indicated to have restriction for the consumption of polyphenols or plant foods)			Usual diet (no changes in the usual diet of the participants or NR)

^a BMI cut-off values as established by the WHO; ^b Includes individuals specifically reported as healthy and not medicated (in some cases medication was not reported, NR); ^c Includes individuals not medicated that were overweight and (or) obese, or specifically indicated to be borderline, mild condition or ‘at risk’ of a disease; ^d Includes individuals with one or more than one of the following disorders: dyslipidemia, glucose disorders or type-2 diabetes, blood pressure disorders (hypertension), medicated obesity, metabolic syndrome (most cases were also medicated but in some cases medication was NR).