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. 2018 Mar 1;19(3):706. doi: 10.3390/ijms19030706

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Gene expression pattern of aged cortical microglia. (A) Workflow scheme depicting microglia isolation and sorting strategy. (B,C) GO term enrichment analysis of biological processes (B) and molecular functions (C) as performed using DAVID Bioinformatics Resources 6.8. (D) Heatmap summarizing transcriptional changes in aged cortical microglia. Expression data from aged microglia are presented as log₂-fold changes (n = 2) and compared to young (6-month-old) microglia. CC = corpus callosum, CPu = caudatoputamen, Ctx = cortex, Thal = thalamus.