Table 6.
The association between H. pylori virulence factors and clinical outcomes.
| No. of Samples | |||||
|---|---|---|---|---|---|
| Type | GU | DU | PU | Gastritis | Total |
| No of culture positive cases | 10 | 6 | 16 | 155 | 171 |
| cagA positive | 10 (100%) | 6 (100%) | 16 (100%) | 154 (99.4%) | 170 (99.4%) |
| Western-type CagA | 4 (40%) | 2 (33.3%) | 6 (37.5%) | 67 (43.2%) | 73 (42.9%) |
| East-Asian-type CagA | 6 (60%) | 4 (66.7%) | 10 (62.5%) | 87 (56.1%) | 97 (57.1%) |
| vacA s1 | 10 (100%) | 6 (100%) | 16 (100%) | 155 (100%) | 171 (100%) |
| vacA m1 | 8 (80%) | 5 (83.3%) | 13 (81.3%) | 99 (63.9%) | 112 (65.5%) |
| vacA m2 | 2 (20%) | 1 (16.7%) | 3 (18.7%) | 54 (34.8%) | 57 (33.3%) |
| vacA m1m2 | 2 (20%) | 0 (0%) | 2 (12.5%) | 2 (1.3%) | 2 (1.2%) |
| vacA s1m1 | 8 (80%) | 5 (83.3%) | 13 (81.3%) | 99 (63.9%) | 112 (65.5%) |
| vacA s1m2 | 2 (20%) | 1 (16.7%) | 0 (0%) | 54 (34.8%) | 57 (33.3%) |
| vacA s1m1m2 | 2 (20%) | 0 (0%) | 0 (0%) | 2 (1.3%) | 2 (1.2%) |
| Western-type CagA/vacA s1m1 | 4 (40%) | 1 (16.7%) | 5 (31.3%) | 58 (37.4%) | 63 (36.8%) |
| Western-type CagA/vacA s1m2 | 0 (0%) | 1 (16.7%) | 1 (6.3%) | 9 (5.8%) | 10 (5.8%) |
| East-Asian-type CagA/vacA s1m1 | 4 (40%) | 4 (66.7%) a | 8 (50%) | 40 (25.8%) a | 48 (28.1%) |
| East-Asian-type CagA/vacA s1m2 | 2 (20%) | 0 (0%) | 0 (0%) | 45 (29%) | 47 (27.5%) |
| East-Asian-type CagA/vacA s1m1m2 | 0 (0%) | 0 (0%) | 0 (0%) | 2 (1.3%) | 2 (1.2%) |
a p = 0.048 by Fisher exact test when compared between DU and gastritis.