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. 2018 Mar 7;19(3):768. doi: 10.3390/ijms19030768

Figure 5.

Figure 5

Models of the complexes of full-length adalimumab and TNFα trimers. The models are derived by fitting a TNFα trimer (blue, pale blue, and cyan) and bound Fab fragments (heavy chain: red, light chain: yellow) of PDB ID 3WD5 to the cryo EM electron density. (A) 1:1 complex; (B) 1:2 complex; (C) 2:2 complex; (D) 3:3 complex.